COVID-19 New Double Mutant fears of spread in 10 states Sources attached to the Ministry of Health say that the double mutant variant is expected to reach 10 states. These include Maharashtra, Delhi, Bengal, Gujarat, Karnataka and Gujarat etc.
New Delhi: The speed of Corona is increasing day by day. The daily figure of the infected has crossed two lakhs. Experts are looking into the causes of the second wave of corona infection. Last week, the National Institute of Virology (NIV) shared some data in a meeting with district laboratories in Maharashtra. Genome sequencing of 361 samples was carried out in the state from January to March, of which 220 (around 61%) were found to have double mutant variants. According to sources, genome sequencing of 1.40 lakh samples has been done across the country.
What is B.1.617 ?
The double mutant variant is classified as B.1.617. Both E484Q and L452R mutations have been found in it. These variants have been found to be different in many countries, but for the first time in India, the two have come together. Both mutations have occurred in the spike proteins of the virus, which facilitate the entry of the virus into human cells. The E484Q mutation is similar to the E484K that was found in the UK (B.1.1.7) and South African (B.1.351) variants. The L452R mutation was first detected in California (B.1.427 and B.1.429), when corona infection began to spread rapidly there. This spike increases the strength of the protein, causing the coronavirus to become more contagious. L452R enhances replication-causing ability in viruses. Being with E484 Q and L452R, the virus becomes more contagious. He is also able to penetrate the immune system.
What’s more dangerous is the new variant found in India ?
No such evidence has been found yet. Most patients are recovering in home isolation. However, it should have a clinical trial with data on genome sequencing for scientific evidence. Experts believe that the double mutant variant spreads faster, is more contagious, and can infect the whole family, but it causes fewer conditions such as hospitalization after infection. Most patients do not show signs of the corona, but an increasing number of them affect health services.
Where it was found for the first time ?
It was first found in Maharashtra. In January, 19 samples were tested from different districts. Four of these were found to be B1.617. In February, 151 samples were tested from 234 and 16 districts taken from 18 districts and this variant was present in all of them. This variant was present in 65 of 94 samples in March.
How much has spread?
Dr. Sujit Singh, director of the National Center for Disease Control (NCDC), says that there has been less sample genome sequencing in Maharashtra. This conclusion cannot be reached as to how widespread the double mutant variant has been. On the other hand, sources related to the Ministry of Health say that genome sequencing of 1.40 lakh samples has been done across the country. The double mutant virus can be attributed to the second wave. However, experts are analyzing the report and nothing can be said in the final.
Can also give vaccine outperform ?
According to experts, there have been some cases of people getting infected after taking the vaccine. However, it is not yet clear whether their samples have been sent for genome sequencing. However, UK and South African variants are known to be more contagious. Experts say that it is not expected that someone will be infected after taking the vaccine, but if someone is infected after vaccination, the chances of the condition becoming serious or death are low.
Fear of spread in 10 states: Sources associated with the Ministry of Health say that the double mutant variant is expected to reach 10 states. These include Maharashtra, Delhi, Bengal, Gujarat, Karnataka, and Gujarat, etc.